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Despite advances in treatment in recent decades, multiple myeloma (MM) is still considered incurable, necessitating the development of newer therapeutic options Triple class refractory patients—those refractory to an immunomodulatory drug (IMiD), a proteasome inhibitor (PI) and an anti-CD38 antibody—have a dismal outcome ( 1 )
- Can Venclexta be used for Multiple Myeloma? - Drugs. com
Although Venclexta is not FDA approved for use in Multiple Myeloma (MM), some research indicates that it may be promising for some MM patients who have failed at least one prior treatment, especially those with the genetic abnormality t(11;14) or with high levels of BCL-2 However, its use is not without controversy One major trial investigating the use of Venclexta for relapsed and
- Venetoclax in Patients with Multiple Myeloma with or without t(11;14 . . .
We included all patients in the Flatiron Health database with multiple myeloma (ICD-9 203 0x or ICD-10 C90 0x, confirmed with clinical review) who had received ven as part of any line of MM treatment This included patients who commenced ven between 2016-2024 The primary endpoint was time to next treatment or death (TTNT) from ven initiation
- Venetoclax for the treatment of multiple myeloma: Outcomes . . . - PubMed
Multiple myeloma (MM) remains an incurable disease despite incorporation of novel agents Venetoclax, a B-cell lymphoma 2 (BCL-2) inhibitor is approved for some hematologic malignancies but not yet for MM, although clinical trials have shown efficacy in patients with MM, particularly those harboring …
- AbbVie Presents Results from Phase 3 CANOVA Study of Venetoclax in . . .
About Multiple Myeloma Multiple myeloma is a type of blood cancer that affects plasma cells, which grow out of control and accumulate in the body's bone marrow 1,4 Multiple myeloma is the second most common blood cancer in the world 1 An estimated 176,000 people globally were diagnosed with multiple myeloma in 2020, About VENCLEXTA
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