DIRECT-MT - The Bottom Line Direct Intraarterial Thrombectomy in Order to Revascularise Acute Ischaemic Stroke Patients with Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals: a Multicentre Randomised Clinical Trial (DIRECT-MT)
TRIAL PROGRESS - DIRECT-MT The DIRECT-MT trial, a multicenter prospective RCT, was published on New England Journal of Medicine (IF=70 67) on 2020-05-07 The chairman was prof Jianmin LIU, the director of Neurosurgery of Changhai hospital affiliated to Naval Medical University
Association of Intravenous Alteplase, Early Reperfusion, and Clinical . . . DIRECT-MT was a randomized controlled trial evalu-ating EVT alone versus combined EVT and intravenous alteplase for acute ischemic stroke patients with large vessel occlusion in the anterior circulation who pre-sented directly to an EVT-capable center The trial results indicated that EVT alone was noninferior to combined
Direct Intra-Arterial Thrombectomy in Order to Revascularize Acute . . . The DIRECT-MT trial showed that among patients with acute ischemic stroke presenting within 4 5 hours of symptom onset due to proximal large arterial occlusion, the use of direct endovascular treatment was noninferior to endovascular treatment along with intravenous thrombolysis
Frontiers | Mild and moderate cardioembolic stroke patients may benefit . . . A total of 290 patients from the DIRECT-MT trial were regarded as cardioembolic LVOs, 146 received direct endovascular thrombectomy alone (direct MT group), and 144 underwent combination therapy with intravenous alteplase and endovascular thrombectomy (bridging therapy group)